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Peer Reviewers: 

Lisa Joan Pfitzer, MD 
Assistant Professor
University of Louisville School of Medicine
Chair, University of Louisville Continuing Medical Education & Professional Development Advisory Board 

Lori Wagner, MD
Associate Professor
University of Louisville School of Medicine 

Dr. Pfitzer and Dr. Wagner have no relevant financial relationships with any commercial interests. 

For CME/CE Credit: 

To earn CME/CE credit: 1) read the program information, including the disclosure statements; 2) read the entire article; 3) correctly answer both post-test questions; 4) complete the evaluation form; and 5) follow the instructions for printing or e-mailing your CME credit certificate. Transcript summaries of your activities or additional copies of certificates are available by clicking the Your CME Activity Transcript button. 

About Click for Credit® 

Provision of the highest-quality medical care requires that clinicians remain up-to-date on important developments in research and practice recommendations. CLICK FOR CREDIT is part of a multi-year initiative to stimulate continuous learning of new developments in the clinical practice of medicine. Articles selected for the CLICK FOR CREDIT educational activity provide a convenient avenue for accessing current information and incorporating relevant concepts into patient care. 

Learning Objectives 

On completing this educational activity, participants should be able to: 

1. Discuss the results of the study or educational presentation addressed in these articles which focus on topics of high clinical interest for the physicians, physician assistants, nurses, nurse practitioners who are in clinical practice. 
2. Review the clinical relevance and practice implications of the information presented. 

Target Audience
This enduring activity is intended for family medicine physicians, internal medicine specialists, related specialists, residents, nurses and other healthcare professionals who are most likely to be consulted for treatment of various diseases and disorders that comprise healthcare in primary care medicine. 

Disclosures: The staff members of Global Academy for Medical Education report that they have no financial disclosures to report. Disclosures relevant to each article are included in or with the individual CLICK FOR CREDIT articles. There is no fee to participate in this activity. Costs associated with this activity are borne by Global Academy for Medical Education as a service to physicians and the healthcare community at large. healthcare community at large. 

This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Louisville and Global Academy for Medical Education. The University of Louisville is accredited by the ACCME to provide continuing education for physicians. 

Designation Statement
The University of Louisville Office of Continuing Medical Education & Professional Development designates this educational activity for a maximum of 0.25 AMA PRA Category 1 Credit(s)™(. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

AMA PRA accreditation begins January 2020. Term of approval is for 1 year from this date. Credit may be claimed for one year. 

This program has been approved by the Kentucky Board of Nursing for 0.3 continuing education credits through University of Louisville Hospital, provider number 4-0068-7-16-811. The Kentucky Board of Nursing approval of an individual nursing education provider does not constitute endorsement of program content. 

Click for Credit articles are originally published by Frontline Medical Communications family of publications ( . 

Copyright © 2020 Global Academy for Medical Education LLC. All rights reserved. No part of this site, and newsletter may be published, broadcast, copied or otherwise reproduced or distributed without the prior written permission from Global Academy for Medical Education. The ideas and opinions expressed in this site, articles and newsletter do not necessarily reflect those of the Publisher or the Joint Providers. Global Academy for Medical Education will not assume responsibility for damages, loss, or claims of any kind arising from or related to the information contained in this publication, including any claims related to the products, drugs, or services mentioned herein. 

Commercial Support
No commercial support was used or received to fund this enduring material.

Hardware & Software Requirements
High speed internet connection
Adobe Acrobat 7.0 or higher
Course content compatible with Mac OS

Course Director and Coordinator
Tristan Nelson has no relevant financial relationships to disclose. 
Planning Committee Members
W. Daniel Cogan, Ed.D., Sylvia Reitman, and Jenny Campano have no relevant financial relationships to disclose. 
Whitney McKnight has no relevant financial relationships to disclose. Additional disclosures relevant to each article are included in or with the individual CLICK FOR CREDIT articles. 
CME & PD Staff and Advisory Board
The CME & PD staff and Advisory Board have nothing to disclose with the exception of DFine, Inc. (Consultant). 

Estimated Time to Complete Activities
Each article takes approximately 15 minutes to complete. 
Original Release & Termination Dates
Medium or combination of media used: Online enduring material activity
Method of Physician Participation: Online articles
Estimated time to complete the educational activity: 15 minutes per article
Course Originally Released On: 1/1/2017
Date of Most Recent Review: 1/1/2019
Course Termination Date: 1/1/2021

Special Services
If you need special accommodations due to a disability, or for an alternative form of course materials, please contact Tristan Nelsen. Continuing Medical Education & Professional Development fully complies with the legal requirements of the ADA and the rules and regulations thereof. 

Provider Contact Information
If you need technical support or have questions about the course, please e-mail us at

Privacy Policy
The University of Louisville's Continuing Medical Education and Professional Development office respects your privacy. Personal information collected from participants of our medical educational activities will not, unless required by law, be shared with any third party. The primary reason we collect your personal information is for accountability and documentation of your continuing education activities in compliance with Accreditation Council for Continuing Medical Education (ACCME) regulations. We do not distribute unsolicited e-mails, nor, unless required by law, do we share the names of our subscribers with any third party.

Study: Complications from childhood ALL and its treatment are common, but can be managed

Despite survival after treatment of acute lymphoblastic leukemia (ALL), a high percentage of children suffered acute complications, even without relapse.


The 5- and 10-year overall survival rates were both 85.9%, while the relapse-free survival rates at 1, 3, and 5 years were 97.9%, 91.3%, and 86.3%, respectively.